Association of Infiltrating Lobular Carcinoma With Positive Surgical Margins After Breast-Conservation Therapy

Surgical Margins in Breast Conservation

Copyright © 2013 Sheldon Marc Feldman. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Signi�cant progress has been made in the diagnosis and treatment of breast cancer during the past 30 years. e increased availability of screeni...

Optimizing Surgical Margins in Breast Conservation

Adequate surgical margins in breast-conserving surgery for breast cancer have traditionally been viewed as a predictor of local recurrence rates. There is still no consensus on what constitutes an adequate surgical margin, however it is clear that there is a trade-off between widely clear margins and acceptable cosmesis. Preoperative approaches to plan extent of resection with appropriate margi...

Surgical margins in breast-conserving therapy

Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-conserving therapy (BCT) for early-stage breast cancer. The majority of studies report positive resection margins in 20% to 40% of the patients who underwent BCT. This may result in an increased local recurrence (LR) rate or additional surgery and, consequently, adverse effects on cosmesis, psychological di...

Infiltrating lobular carcinoma: four case illustrations.

Medullary thyroid carcinoma metastatic to breast masquerading as infiltrating lobular carcinoma.

Metastatic tumors to the breast from an extramammary site are rare entities and may present diagnostic difficulties for the surgical pathologist because of frequent histological similarities to primary neoplasms in this location. A case is reported of medullary thyroid carcinoma metastatic to the breast in a 28-year-old woman with a family history of MEN IIA (Sipple's) syndrome. Histological fe...